MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02753nam a2200397Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
3228 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20260820085646.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
210817s9999 xx 000 0 und d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780132 064521 |
| Qualifying information |
Hardcover. |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
RDA |
| Language of cataloging |
ENGLISH |
| Transcribing agency |
3228 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
540 PETR |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Petrucci, ralph H. Toronto, Ont., [c.2011] 10th ed |
| Dates associated with a name |
2011. |
| Relator term |
Author. |
| 111 ## - MAIN ENTRY--MEETING NAME |
|---|
| 9 (RLIN) |
178758 |
| Meeting name or jurisdiction name as entry element |
Bible Society of South Africa |
| 245 #0 - TITLE STATEMENT |
|---|
| Title |
General chemistry: |
| Remainder of title |
principles and modern applications |
| Statement of responsibility, etc. |
Ralph H. Petrucci [and others]. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
10th ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Toronto, Ont.: |
| Name of publisher, distributor, etc. |
Pearson Canada, |
| Date of publication, distribution, etc. |
2011. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
xxiv, 1303 pages |
| Other physical details |
Colour illustrations: |
| Dimensions |
28 cm |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Includes index. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The Molecule on the Front Cover is Paclitaxel, C47H51NO14 a chemotherapy drug that has been successful in treating breast, lung, and ovatian cancer. It is extracted from the bark of the Pacific Yew tree (Taxus brevifolia). Unfortunately, the bark of a 100-year-old Pacific Yew tree yields about 3 kg of bark and only 300 mg of paclitaxel, barely enough for a single dose of the drug (Taxol).The synthesis of this molecule engaged the attention of chemists for more than 20 years until finally, in 1994, chemists from Florida State University and from the University of California (San Diego) announced independently that they were able to synthesize it from simpler and readily available starting materials. A major challenge in the synthesis of paclitaxel is getting the spatial arrangement of atoms around 11 of the carbon atoms just right. These 11 carbon atoms are identified in the ball-and-stick structure by green or purple circles. If the synthesis is not done carefully, up to 2048 different possible paclitaxel-like structures could be obtained, but only one is known to have the desired anti-tumor activity. Because chemists can now synthesize paclitaxel, it is possible for researchers to explore how it works and design new chemotherapeutic drugs that are safer and more effective. --Book Jacket. |
| 521 ## - TARGET AUDIENCE NOTE |
|---|
| Target audience note |
Adult. |
| 600 #0 - SUBJECT ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
8190 |
| Personal name |
Petrucci, Ralph H. Toronto, Ont., [c.2011] 10th ed |
| Dates associated with a name |
2011. |
| Fuller form of name |
Author. |
| 610 #0 - SUBJECT ADDED ENTRY--CORPORATE NAME |
|---|
| 9 (RLIN) |
176682 |
| Corporate name or jurisdiction name as entry element |
Pearson |
| 630 #0 - SUBJECT ADDED ENTRY--UNIFORM TITLE |
|---|
| 9 (RLIN) |
178919 |
| Uniform title |
Critical world issues |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
197108 |
| Topical term or geographic name entry element |
Natural Science |
| 651 #0 - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
|---|
| 9 (RLIN) |
196576 |
| Geographic name |
South Africa |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS |
|---|
| 9 (RLIN) |
181703 |
| Focus term |
Problems and exercises |
| 655 #0 - INDEX TERM--GENRE/FORM |
|---|
| 9 (RLIN) |
181968 |
| Genre/form data or focus term |
Adult Non-Fiction |
| 658 ## - INDEX TERM--CURRICULUM OBJECTIVE |
|---|
| 9 (RLIN) |
176459 |
| Main curriculum objective |
Earth sciences |
| 662 ## - SUBJECT ADDED ENTRY--HIERARCHICAL PLACE NAME |
|---|
| 9 (RLIN) |
186049 |
| Country or larger entity |
United States |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) |
|---|
| 9 (RLIN) |
186867 |
| Topical term or geographic name as entry element |
Chemistry |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
8190 |
| Personal name |
Petrucci, Ralph H. Toronto, Ont., [c.2011] 10th ed |
| Dates associated with a name |
2011. |
| Relator term |
Author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
187737 |
| Personal name |
HERRING F GEOFFREY |
| Dates associated with a name |
2011. |
| Relator term |
Author. |
| 710 ## - ADDED ENTRY--CORPORATE NAME |
|---|
| 9 (RLIN) |
176682 |
| Corporate name or jurisdiction name as entry element |
Pearson |
| 711 ## - ADDED ENTRY--MEETING NAME |
|---|
| 9 (RLIN) |
178758 |
| Meeting name or jurisdiction name as entry element |
Bible Society of South Africa |
| 942 ## - ADDED ENTRY ELEMENTS |
|---|
| item type |
Book |
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| -- |
559 |
| -- |
Nosiswe Mogale |